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Le modafinil agit en augmentant la production cГ©rГ©brale de ces neurotransmetteurs. Il est disponible en gГ©lules de 100 mg, 200 mg, 300 mg, 400 mg et 800 mg. Modafinil fonctionne en inhibant le sous-type de rГ©cepteur A2A, qui est un rГ©cepteur couplГ© aux protГ©ines G. Le modafinil a ensuite Г©tГ© reclassГ© comme "stimulant du SNC" par la FDA. Le mГ©dicament peut ГЄtre initiГ© Г  faible dose et augmentГ© au besoin.

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Il est Г©galement dГ©conseillГ© aux personnes souffrant de problГЁmes rГ©naux ou hГ©patiques. Le modafinil peut ГЄtre utilisГ© pour traiter la somnolence diurne excessive et la fatigue (EDS/EF). Modafinil a Г©tГ© dГ©veloppГ© Г  l'origine comme traitement de la narcolepsie.

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Le brevet Г©tait initialement dГ©tenu conjointement par les Laboratoires Lafon et Michel Jouvet. Le modafinil est un mГ©dicament psychostimulant qui a Г©tГ© dГ©veloppГ© Г  l'origine pour traiter la narcolepsie. DurГ©e des effets.

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Certaines personnes qui utilisent le modafinil n'ont pas beaucoup d'effets secondaires. Chez les personnes atteintes de narcolepsie, les taux sont dГ©jГ  Г©levГ©s et le modafinil n'a aucun effet. Le lactose, l'acide citrique et le talc peuvent ГЄtre omis de la formulation originale pour fabriquer un comprimГ© sans sucre et plus agrГ©able au goГ»t. Dans les Г©tudes animales, le modafinil a diminuГ© la durГ©e du sommeil et augmentГ© la durГ©e de l'Г©veil sans affecter la durГ©e du sommeil non paradoxal. Des recherches rГ©centes ont cherchГ© Г  trouver des gГЁnes impliquГ©s dans le mГ©tabolisme du modafinil.

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Le modafinil et un dГ©rivГ© de sa structure chimique appelГ© armodafinil sont les noms commerciaux de ce mГ©dicament. Le mГ©canisme d'action exact n'est pas clair. Cela peut entraГ®ner des Г©vГ©nements indГ©sirables. Si votre tension artГ©rielle est dГ©jГ  Г©levГ©e, ne prenez pas ce mГ©dicament.

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Les directives de dosage liГ©es Г  l'Гўge sont les suivantes : 1-12 mois : non recommandГ© ; 1-5 ans : non recommandГ© ; 6-17 ans : recommandГ© Г  100 mg ; 18-35 ans : recommandГ© Г  100 mg ; 36-65 ans : recommandГ© Г  100 mg ou 200 mg ; et 65 ans et plus : recommandГ© Г  100 mg ou 200 mg. Bien que son Г©tiquette ait Г©tГ© rГ©visГ©e Г  plusieurs reprises, son efficacitГ© clinique a Г©tГ© constamment dГ©montrГ©e dans de multiples essais contrГґlГ©s randomisГ©s. Le modafinil est Г©galement approuvГ© pour traiter la somnolence diurne excessive associГ©e Г  l'apnГ©e obstructive du sommeil. Son dГ©but d'action est gГ©nГ©ralement d'environ deux heures, le plein effet de son action durant huit Г  dix heures.

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